CONTROL OF ISOCITRATASE FORMATION IN RHIZOPUS NIGRICANS

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Control of malate synthase formation in Rhizopus nigricans.

The control of malate synthase formation in a fumaric acid-producing strain of Rhizopus nigricans has been found to be similar in most respects to that of isocitrate lyase, the companion enzyme of the glyoxylate bypass. A basal level is formed in a casein hydrolysate medium, which is repressed by glucose. Utilization of glucose during growth results in relief of glucose repression. Any factor w...

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Mechanism of fumaric acid accumulation in Rhizopus nigricans.

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The formation of isocitratase by the Athiorhodaceae.

Isocitratase, which cleaves isocitrate to glyoxylate and succinate and is a key enzyme in the glyoxylate cycle, is formed by Rhodopseudomonas palustris and R. capsulatus when grown on acetate or butyrate either anaerobically in light or aerobically in the dark. Only traces of the enzyme are present in organisms grown on succinate or malate. In contrast, isocitratase is detectable in traces only...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1964

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.87.1.156-161.1964